Biophysical basis of filamentous phage tactoid-mediated antibiotic tolerance in P. aeruginosa

Biophysical basis of filamentous phage tactoid-mediated antibiotic tolerance in P. aeruginosa

Abstract Inoviruses are filamentous phages infecting numerous prokaryotic phyla. Inoviruses can self-assemble into mesoscale structures with liquid-crystalline order, termed tactoids, which protect bacterial cells in Pseudomonas aeruginosa biofilms from antibiotics. Here, we investigate the structur...

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Bibliographic Details
Main Authors: Jan Böhning, Miles Graham, Suzanne C. Letham, Luke K. Davis, Ulrike Schulze, Phillip J. Stansfeld, Robin A. Corey, Philip Pearce, Abul K. Tarafder, Tanmay A. M. Bharat
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-44160-8

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https://doi.org/10.1038/s41467-023-44160-8

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