Cytotoxic Activity of α-Aminophosphonic Derivatives Coming from the Tandem Kabachnik–Fields Reaction and Acylation

Encouraged by the significant cytotoxic activity of simple α-aminophosphonates, a molecular library comprising phosphonoylmethyl- and phosphinoylmethyl-α-aminophosphonates, a tris derivative, and <i>N</i>-acylated species was established. The promising aminophosphonate derivatives were s...

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Bibliographic Details
Main Authors: Petra R. Varga, Rita Oláhné Szabó, György Dormán, Szilvia Bősze, György Keglevich
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/16/4/506