Microglial Over-Activation by Social Defeat Stress Contributes to Anxiety- and Depressive-Like Behaviors

Hyper activation of the neuroimmune system is strongly related to the development of neuropsychiatric disorders. Psychosocial stress has been postulated to play an important role in triggering anxiety and major depression. In preclinical models, there is mounting evidence that social defeat stress a...

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Bibliographic Details
Main Authors: Dirson J. Stein, Mailton F. Vasconcelos, Lucas Albrechet-Souza, Keila M. M. Ceresér, Rosa M. M. de Almeida
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fnbeh.2017.00207/full