Intensive systolic blood pressure treatment remodels brain perivascular spaces: A secondary analysis of the Systolic Pressure Intervention Trial (SPRINT)

Background: Brain perivascular spaces (PVS) are part of the glymphatic system and facilitate clearance of metabolic byproducts. Since enlarged PVS are associated with vascular health, we tested whether intensive systolic blood pressure (SBP) treatment affects PVS structure. Methods: This is a second...

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Bibliographic Details
Main Authors: Kyle C. Kern, Ilya M. Nasrallah, Robert Nick Bryan, David M. Reboussin, Clinton B. Wright
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:NeuroImage: Clinical
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158223002048