Physicochemical Properties and Transdermal Absorption of a Flurbiprofen and Lidocaine Complex in the Non-Crystalline Form

Physicochemical Properties and Transdermal Absorption of a Flurbiprofen and Lidocaine Complex in the Non-Crystalline Form

Amorphous drug formulations exploiting drug–drug interactions have been extensively studied. This study aims to develop a transdermal system containing an amorphous complex of the nonsteroidal anti-inflammatory drug (NSAID) flurbiprofen (FLU) and lidocaine (LDC) for alleviating chronic pain. The hig...

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Bibliographic Details
Main Authors: Qihui Xu, Takayuki Furuishi, Kaori Fukuzawa, Etsuo Yonemochi
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Pharmaceutics
Subjects:
flurbiprofen
lidocaine
molecular complex
amorphous
transdermal
Online Access:https://www.mdpi.com/1999-4923/15/2/318

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https://www.mdpi.com/1999-4923/15/2/318

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