Proteome profiling of whole plasma and plasma-derived extracellular vesicles facilitates the detection of tissue biomarkers in the non-obese diabetic mouse

The mechanism by which pancreatic beta cells are destroyed in type 1 diabetes (T1D) remains to be fully understood. Recent observations indicate that the disease may arise because of different pathobiological mechanisms (endotypes). The discovery of one or several protein biomarkers measurable in re...

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Bibliographic Details
Main Authors: Isabel M. Diaz Lozano, Helena Sork, Virginia M. Stone, Maria Eldh, Xiaofang Cao, Maria Pernemalm, Susanne Gabrielsson, Malin Flodström-Tullberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.971313/full