A Novel Benzopyrane Derivative Targeting Cancer Cell Metabolic and Survival Pathways

A Novel Benzopyrane Derivative Targeting Cancer Cell Metabolic and Survival Pathways

(1) Background: Today, the discovery of novel anticancer agents with multitarget effects and high safety margins represents a high challenge. Drug discovery efforts indicated that benzopyrane scaffolds possess a wide range of pharmacological activities. This spurs on building a skeletally diverse li...

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Bibliographic Details
Main Authors: Dana M. Zaher, Wafaa S. Ramadan, Raafat El-Awady, Hany A. Omar, Fatema Hersi, Vunnam Srinivasulu, Ibrahim Y. Hachim, Farah I. Al-Marzooq, Cijo G. Vazhappilly, Salim Merali, Carmen Merali, Nelson C. Soares, Paul Schilf, Saleh M. Ibrahim, Taleb H. Al-Tel
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
multitarget
apoptosis
DNA damage
cell cycle
thioredoxin reductase
glutathione reductase
Online Access:https://www.mdpi.com/2072-6694/13/11/2840

Internet

https://www.mdpi.com/2072-6694/13/11/2840

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