Serum N-propeptide of collagen IIA (PIIANP) as a marker of radiographic osteoarthritis burden.

OBJECTIVE:Cartilage homeostasis relies on a balance of catabolism and anabolism of cartilage matrix. Our goal was to evaluate the burden of radiographic osteoarthritis and serum levels of type IIA procollagen amino terminal propeptide (sPIIANP), a biomarker representing type II collagen synthesis, i...

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Bibliographic Details
Main Authors: Hikmat N Daghestani, Joanne M Jordan, Jordan B Renner, Michael Doherty, A Gerry Wilson, Virginia B Kraus
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5747482?pdf=render