Severe drug-induced repetitive behaviors and striatal overexpression of VAChT in ChAT-ChR2-EYFP BAC transgenic mice

Severe drug-induced repetitive behaviors and striatal overexpression of VAChT in ChAT-ChR2-EYFP BAC transgenic mice

In drug users, drug-related cues alone can induce dopamine release in the dorsal striatum. Instructive cues activate inputs to the striatum from both dopaminergic and cholinergic neurons, which are thought to work together to support motor learning and motivated behaviors. Imbalances in these neurom...

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Bibliographic Details
Main Authors: Jill R Crittenden, Carolyn J Lacey, Tyrone eLee, Hilary A Bowden, Ann M Graybiel
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Neural Circuits
Subjects:
Acetylcholine
Amphetamine
Basal Ganglia
Dopamine
Striatum
drug addiction
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncir.2014.00057/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncir.2014.00057/full

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