Epigenetic regulation of TP53 is involved in prostate cancer radioresistance and DNA damage response signaling

Epigenetic regulation of TP53 is involved in prostate cancer radioresistance and DNA damage response signaling

Abstract External beam radiotherapy (RT) is a leading first-line therapy for prostate cancer (PCa), and, in recent years, significant advances have been accomplished. However, RT resistance can arise and result in long-term recurrence or disease progression in the worst-case scenario. Thus, making c...

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Bibliographic Details
Main Authors: Catarina Macedo-Silva, Vera Miranda-Gonçalves, Nuno Tiago Tavares, Daniela Barros-Silva, Joana Lencart, João Lobo, Ângelo Oliveira, Margareta P. Correia, Lucia Altucci, Carmen Jerónimo
Format: Article
Language:English
Published: Nature Publishing Group 2023-10-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-023-01639-6

Internet

https://doi.org/10.1038/s41392-023-01639-6

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