Density distribution of gene expression profiles and evaluation of using maximal information coefficient to identify differentially expressed genes.

The hypothesis of data probability density distributions has many effects on the design of a new statistical method. Based on the analysis of a group of real gene expression profiles, this study reveal that the primary density distributions of the real profiles are normal/log-normal and t distributi...

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Bibliographic Details
Main Authors: Han-Ming Liu, Dan Yang, Zhao-Fa Liu, Sheng-Zhou Hu, Shen-Hai Yan, Xian-Wen He
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0219551