The pUL37 tegument protein guides alpha-herpesvirus retrograde axonal transport to promote neuroinvasion.

The pUL37 tegument protein guides alpha-herpesvirus retrograde axonal transport to promote neuroinvasion.

A hallmark property of the neurotropic alpha-herpesvirinae is the dissemination of infection to sensory and autonomic ganglia of the peripheral nervous system following an initial exposure at mucosal surfaces. The peripheral ganglia serve as the latent virus reservoir and the source of recurrent inf...

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Bibliographic Details
Main Authors: Alexsia L Richards, Patricia J Sollars, Jared D Pitts, Austin M Stults, Ekaterina E Heldwein, Gary E Pickard, Gregory A Smith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5749899?pdf=render

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http://europepmc.org/articles/PMC5749899?pdf=render

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