Expression of hereditary hemochromatosis C282Y HFE protein in HEK293 cells activates specific endoplasmic reticulum stress responses

<p>Abstract</p> <p>Background</p> <p>Hereditary Hemochromatosis (HH) is a genetic disease associated with iron overload, in which individuals homozygous for the mutant C282Y <it>HFE </it>associated allele are at risk for the development of a range of disorde...

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Bibliographic Details
Main Authors: Norris Suzanne, O'Dwyer Michael J, White Mary, Mankan Arun K, Lawless Matthew W
Format: Article
Language:English
Published: BMC 2007-07-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/8/30