Mechanochemical synthesis of indolyl chalcones with antiproliferative activity

An efficient eco-friendly one-step mechanochemical synthesis of indole hybrid chalcones via the Claisen–Schmidt condensation of 1-methylindole-3-carboxaldehyde with various substituted acetophenones is described using liquid assisted grinding in a high-energy ball mill. The notable advantages of the...

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Bibliographic Details
Main Authors: Zuzana Kudličková, Martin Stahorský, Radka Michalková, Mária Vilková, Matej Baláž
Format: Article
Language:English
Published: Taylor & Francis Group 2022-04-01
Series:Green Chemistry Letters and Reviews
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/17518253.2022.2089061