Exploring the relationship between Treg-mediated risk in COPD and lung cancer through Mendelian randomization analysis and scRNA-seq data integration

Exploring the relationship between Treg-mediated risk in COPD and lung cancer through Mendelian randomization analysis and scRNA-seq data integration

Abstract Background Evidence from observational studies suggests an association between chronic obstructive pulmonary disease (COPD) and lung cancer. The potential interactions between the immune system and the lungs may play a causative role in COPD and lung cancer and offer therapeutic prospects....

Full description

Bibliographic Details
Main Authors: Dengfeng Zhang, Haitao Liu, Fangchao Zhao, Pengfei Guo, Jing Li, Tianxing Lu, Zhirong Li, Shujun Li
Format: Article
Language:English
Published: BMC 2024-04-01
Series:BMC Cancer
Subjects:
scRNA-seq
Mendelian randomization
Lung cancer
Regulatory T cells
Chronic obstructive Pulmonary disease
Online Access:https://doi.org/10.1186/s12885-024-12076-1

Internet

https://doi.org/10.1186/s12885-024-12076-1

Similar Items