Effect of ion-exchange chromatography on removal of fibronectin in von Willebrand factor

Objective To study the removal effect of fibronectin(Fn) from von willebrand factor(vWF) by ion-exchange chromatography through processing human coagulation factor Ⅷ chromatographic washing products, in order to select a method that can effectively reduce Fn without compromising the activity yield....

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Bibliographic Details
Main Authors: Zheng ZHOU, Xuecheng ZHANG, Minghua WANG, Jiawen LI, Xiaowei MA
Format: Article
Language:zho
Published: Institute of Blood Transfusion of Chinese Academy of Medical Sciences 2023-03-01
Series:Zhongguo shuxue zazhi
Subjects:
Online Access:https://www.cjbt.cn/thesisDetails#10.13303/j.cjbt.issn.1004-549x.2023.03.019&lang=en