LSD1: an emerging face in altering the tumor microenvironment and enhancing immune checkpoint therapy

LSD1: an emerging face in altering the tumor microenvironment and enhancing immune checkpoint therapy

Abstract Dysregulation of various cells in the tumor microenvironment (TME) causes immunosuppressive functions and aggressive tumor growth. In combination with immune checkpoint blockade (ICB), epigenetic modification-targeted drugs are emerging as attractive cancer treatments. Lysine-specific demet...

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Bibliographic Details
Main Authors: M A A Mamun, Yu Zhang, Jin-Yuan Zhao, Dan-Dan Shen, Ting Guo, Yi-Chao Zheng, Li-Juan Zhao, Hong-Min Liu
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Journal of Biomedical Science
Subjects:
LSD1
Tumor microenvironment
Immunosuppression
Immune checkpoint blockade
Epigenetic TME regulation
Online Access:https://doi.org/10.1186/s12929-023-00952-0

Internet

https://doi.org/10.1186/s12929-023-00952-0

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