Innate Anti-microbial and Anti-chemotaxis Properties of Progranulin in an Acute Otitis Media Mouse Model

Innate Anti-microbial and Anti-chemotaxis Properties of Progranulin in an Acute Otitis Media Mouse Model

Acute otitis media (AOM) is one of the most common infectious diseases primarily caused by Streptococcus pneumoniae (S.pn) among children. Progranulin (PGRN) is a multifunctional growth factor widely expressed in various tissues and cells. Studies have confirmed that PGRN is involved in the developm...

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Bibliographic Details
Main Authors: Zimeng Wang, Qian He, Xinxin Zhang, Yurong Ma, Fangmei Fan, Yilin Dong, Wenchun Xu, Yibing Yin, Yujuan He
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Immunology
Subjects:
progranulin
Streptococcus pneumoniae
otitis media
chemokine (C-C motif) ligand 2
phagocytosis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02952/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02952/full

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