DenseUNets with feedback non-local attention for the segmentation of specular microscopy images of the corneal endothelium with guttae

Abstract Corneal guttae, which are the abnormal growth of extracellular matrix in the corneal endothelium, are observed in specular images as black droplets that occlude the endothelial cells. To estimate the corneal parameters (endothelial cell density [ECD], coefficient of variation [CV], and hexa...

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Bibliographic Details
Main Authors: Juan P. Vigueras-Guillén, Jeroen van Rooij, Bart T. H. van Dooren, Hans G. Lemij, Esma Islamaj, Lucas J. van Vliet, Koenraad A. Vermeer
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-18180-1