A SNaPshot assay for the rapid and simple detection of four common hotspot codon mutations in the <it>PIK3CA </it>gene

<p>Abstract</p> <p>Background</p> <p>Activating mutations in the <it>PIK3CA </it>gene have been identified in a variety of human malignancies and are commonly detected in hotspot codons located in the helical and kinase domains in exons 9 and 20. Existing me...

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Bibliographic Details
Main Authors: Zwarthoff Ellen C, Hafner Christian, Zuiverloon Tahlita CM, Hurst Carolyn D, Knowles Margaret A
Format: Article
Language:English
Published: BMC 2009-04-01
Series:BMC Research Notes
Online Access:http://www.biomedcentral.com/1756-0500/2/66