Synthesis and Acaricidal Activities of Scopoletin Phenolic Ether Derivatives: QSAR, Molecular Docking Study and in Silico ADME Predictions

Synthesis and Acaricidal Activities of Scopoletin Phenolic Ether Derivatives: QSAR, Molecular Docking Study and in Silico ADME Predictions

Thirty phenolic ether derivatives of scopoletin modified at the 7-hydroxy position were synthesized, and their structures were confirmed by IR, 1H-NMR, 13C-NMR, MS and elemental analysis. Preliminary acaricidal activities of these compounds against female adults of Tetranychus cinnabarinus (Boisduva...

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Bibliographic Details
Main Authors: Jinxiang Luo, Ting Lai, Tao Guo, Fei Chen, Linli Zhang, Wei Ding, Yongqiang Zhang
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Molecules
Subjects:
scopoletin
acaricidal activity
QSAR
molecular docking
ADME properties
Online Access:http://www.mdpi.com/1420-3049/23/5/995

Internet

http://www.mdpi.com/1420-3049/23/5/995

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