Leucine Repeat Rich Kinase 1 Controls Osteoclast Activity by Managing Lysosomal Trafficking and Secretion
We previously demonstrated that mice with targeted deletion of the leucine repeat rich kinase 1 (<i>Lrrk1</i>) gene were osteopetrotic due to the failure of osteoclasts to resorb bone. To determine how LRRK1 regulates osteoclast activity, we examined the intracellular and extracellular a...
| 主要な著者: | , , , , , , , , |
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| フォーマット: | 論文 |
| 言語: | English |
| 出版事項: |
MDPI AG
2023-03-01
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| シリーズ: | Biology |
| 主題: | |
| オンライン･アクセス: | https://www.mdpi.com/2079-7737/12/4/511 |