Comparative analysis of adeno-associated virus serotypes for gene transfer in organotypic heart slices
Abstract Background Vectors derived from adeno-associated viruses (AAVs) are widely used for gene transfer both in vitro and in vivo and have gained increasing interest as shuttle systems to deliver therapeutic genes to the heart. However, there is little information on their tissue penetration and...
Main Authors: | Zihou Liu, Kristin Klose, Sebastian Neuber, Meng Jiang, Manfred Gossen, Christof Stamm |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-11-01
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Series: | Journal of Translational Medicine |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12967-020-02605-4 |
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