Improvement in Solubility and Absorption of Nifedipine Using Solid Solution: Correlations between Surface Free Energy and Drug Dissolution

Ternary solid solutions composed of nifedipine (NDP), amino methacrylate copolymer (AMCP), and polysorbate (PS) 20, 60, or 65 were prepared using a solvent evaporation method. The dissolution profiles of NDP were used to study the effect of the addition of polysorbate based on hydrophilic properties...

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Bibliographic Details
Main Authors: Sukannika Tubtimsri, Yotsanan Weerapol
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/13/17/2963