Potentiating TRPA1 by Sea Anemone Peptide Ms 9a-1 Reduces Pain and Inflammation in a Model of Osteoarthritis

Potentiating TRPA1 by Sea Anemone Peptide Ms 9a-1 Reduces Pain and Inflammation in a Model of Osteoarthritis

Progressive articular surface degradation during arthritis causes ongoing pain and hyperalgesia that lead to the development of functional disability. TRPA1 channel significantly contributes to the activation of sensory neurons that initiate neurogenic inflammation and mediates pain signal transduct...

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Bibliographic Details
Main Authors: Ekaterina E. Maleeva, Yulia A. Palikova, Viktor A. Palikov, Vitaly A. Kazakov, Maria A. Simonova, Yulia A. Logashina, Nadezhda V. Tarasova, Igor A. Dyachenko, Yaroslav A. Andreev
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Marine Drugs
Subjects:
arthritis
TRPA1
TRPV1
peptide
Ms9a-1
inflammation
Online Access:https://www.mdpi.com/1660-3397/21/12/617

Internet

https://www.mdpi.com/1660-3397/21/12/617

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