NDR Kinases Are Essential for Somitogenesis and Cardiac Looping during Mouse Embryonic Development.

NDR Kinases Are Essential for Somitogenesis and Cardiac Looping during Mouse Embryonic Development.

Studies of mammalian tissue culture cells indicate that the conserved and distinct NDR isoforms, NDR1 and NDR2, play essential cell biological roles. However, mice lacking either Ndr1 or Ndr2 alone develop normally. Here, we studied the physiological consequences of inactivating both NDR1 and NDR2 i...

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Bibliographic Details
Main Authors: Debora Schmitz-Rohmer, Simone Probst, Zhong-Zhou Yang, Frédéric Laurent, Michael B Stadler, Aimée Zuniga, Rolf Zeller, Debby Hynx, Brian A Hemmings, Alexander Hergovich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4549247?pdf=render

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http://europepmc.org/articles/PMC4549247?pdf=render

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