Alpha Radiation as a Way to Target Heterochromatic and Gamma Radiation-Exposed Breast Cancer Cells

Alpha Radiation as a Way to Target Heterochromatic and Gamma Radiation-Exposed Breast Cancer Cells

Compact chromatin is linked to a poor tumour prognosis and resistance to radiotherapy from photons. We investigated DNA damage induction and repair in the context of chromatin structure for densely ionising alpha radiation as well as its therapeutic potential. Chromatin opening by histone deacetylas...

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Bibliographic Details
Main Authors: Maja Svetličič, Anton Bomhard, Christoph Sterr, Fabian Brückner, Magdalena Płódowska, Halina Lisowska, Lovisa Lundholm
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cells
Subjects:
alpha radiation
gamma radiation
chromatin
DNA damage
breast cancer
Online Access:https://www.mdpi.com/2073-4409/9/5/1165

Internet

https://www.mdpi.com/2073-4409/9/5/1165

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