Optimising classification of Parkinson’s disease based on motor, olfactory, neuropsychiatric and sleep features

Optimising classification of Parkinson’s disease based on motor, olfactory, neuropsychiatric and sleep features

Abstract Olfactory loss, motor impairment, anxiety/depression, and REM-sleep behaviour disorder (RBD) are prodromal Parkinson’s disease (PD) features. PD risk prediction models typically dichotomize test results and apply likelihood ratios (LRs) to scores above and below cut-offs. We investigate whe...

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Bibliographic Details
Main Authors: Jonathan P. Bestwick, Stephen D. Auger, Anette E. Schrag, Donald G. Grosset, Sofia Kanavou, Gavin Giovannoni, Andrew J. Lees, Jack Cuzick, Alastair J. Noyce
Format: Article
Language:English
Published: Nature Portfolio 2021-09-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-021-00226-2

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https://doi.org/10.1038/s41531-021-00226-2

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