Multivariable risk prediction can greatly enhance the statistical power of clinical trial subgroup analysis

<p>Abstract</p> <p>Background</p> <p>When subgroup analyses of a positive clinical trial are unrevealing, such findings are commonly used to argue that the treatment's benefits apply to the entire study population; however, such analyses are often limited by poor s...

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Bibliographic Details
Main Authors: Kent David M, Hayward Rodney A, Vijan Sandeep, Hofer Timothy P
Format: Article
Language:English
Published: BMC 2006-04-01
Series:BMC Medical Research Methodology
Online Access:http://www.biomedcentral.com/1471-2288/6/18