FMR1 expression in human granulosa cells increases with exon 1 CGG repeat length depending on ovarian reserve
Abstract Background Fragile-X-Mental-Retardation-1- (FMR1)-gene is supposed to be a key gene for ovarian reserve and folliculogenesis. It contains in its 5’-UTR a triplet-base-repeat (CGG), that varies between 26 and 34 in general population. CGG-repeat-lengths with 55–200 repeats (pre-mutation = PM...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-07-01
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Series: | Reproductive Biology and Endocrinology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12958-018-0383-5 |