Tissue niche occupancy determines the contribution of fetal- versus bone-marrow-derived macrophages to IgG effector functions

Tissue niche occupancy determines the contribution of fetal- versus bone-marrow-derived macrophages to IgG effector functions

Summary: Understanding the mechanisms underlying cytotoxic immunoglobulin G (IgG) activity is critical for improving therapeutic antibody activity and inhibiting autoantibody-mediated tissue pathology. While prior research highlights the important role of the mononuclear phagocytic system for removi...

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Bibliographic Details
Main Authors: Miriam Wöhner, Sarah Brechtelsbauer, Niklas Friedrich, Christof Vorsatz, Johanna Bulang, Chunguang Liang, Lena Schorr, Alain Beschin, Martin Guilliams, Jeffrey Ravetch, Falk Nimmerjahn, Markus Biburger
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724000858

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http://www.sciencedirect.com/science/article/pii/S2211124724000858

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