From circRNAs to fusion circRNAs in hematological malignancies
Circular RNAs (circRNAs) represent a type of endogenous noncoding RNA generated by back-splicing events. Unlike the majority of RNAs, circRNAs are covalently closed, without a 5′ end or a 3′ poly(A) tail. A few circRNAs can be associated with polysomes, suggesting a protein-coding potential. CircRNA...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Clinical investigation
2021-11-01
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Series: | JCI Insight |
Online Access: | https://doi.org/10.1172/jci.insight.151513 |