Impaired beta-adrenergic response and decreased L-type calcium current of hypertrophied left ventricular myocytes in postinfarction heart failure

Impaired beta-adrenergic response and decreased L-type calcium current of hypertrophied left ventricular myocytes in postinfarction heart failure

Infarct-induced heart failure is usually associated with cardiac hypertrophy and decreased ß-adrenergic responsiveness. However, conflicting results have been reported concerning the density of L-type calcium current (I Ca(L)), and the mechanisms underlying the decreased ß-adrenergic inotropic respo...

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Bibliographic Details
Main Authors:	R.M. Saraiva, N.G.B. Chedid, C.C. Quintero H., L.E. Díaz G., M.O. Masuda
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2003-05-01
Series:	Brazilian Journal of Medical and Biological Research
Subjects:	Ca2+ channel Heart failure Hypertrophy Infarction Adrenergic receptor
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000500012

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