SIRT3 Enhances Glycolysis and Proliferation in SIRT3-Expressing Gastric Cancer Cells.

SIRT3 is a key NAD+-dependent protein deacetylase in the mitochondria of mammalian cells, functioning to prevent cell aging and transformation via regulation of mitochondrial metabolic homeostasis. However, SIRT3 is also found to express in some human tumors; its role in these SIRT3-expressing tumor...

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Bibliographic Details
Main Authors: Yang Cui, Lili Qin, Jing Wu, Xuan Qu, Chen Hou, Wenyan Sun, Shiyong Li, Andrew T M Vaughan, Jian Jian Li, Jiankang Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4487898?pdf=render