Large-Scale Screening of HCMV-Seropositive Blood Donors Indicates that HCMV Effectively Escapes from Antibodies by Cell-Associated Spread

Large-Scale Screening of HCMV-Seropositive Blood Donors Indicates that HCMV Effectively Escapes from Antibodies by Cell-Associated Spread

Immunoglobulins are only moderately effective for the treatment of human cytomegalovirus (HCMV) infections, possibly due to ineffectiveness against cell-associated virus spread. To overcome this limitation, we aimed to identify individuals with exceptional antibodies in their plasma that can efficie...

Full description

Bibliographic Details
Main Authors: Jessica Julia Falk, Martina Winkelmann, Kerstin Laib Sampaio, Caroline Paal, Hubert Schrezenmeier, Mira Alt, Richard Stanton, Adalbert Krawczyk, Ramin Lotfi, Christian Sinzger
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Viruses
Subjects:
cytomegalovirus
antibodies
cell-associated spread
immune evasion
Online Access:http://www.mdpi.com/1999-4915/10/9/500

Internet

http://www.mdpi.com/1999-4915/10/9/500

Similar Items