Novel Tyrosine Kinase-Mediated Phosphorylation With Dual Specificity Plays a Key Role in the Modulation of Streptococcus pyogenes Physiology and Virulence

Novel Tyrosine Kinase-Mediated Phosphorylation With Dual Specificity Plays a Key Role in the Modulation of Streptococcus pyogenes Physiology and Virulence

Streptococcus pyogenes (Group A Streptococcus, GAS) genomes do not contain a gene encoding a typical bacterial-type tyrosine kinase (BY-kinase) but contain an orphan gene-encoding protein Tyr-phosphatase (SP-PTP). Hence, the importance of Tyr-phosphorylation is underappreciated and not recognized fo...

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Bibliographic Details
Main Authors: Sashi Kant, Vijay Pancholi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Microbiology
Subjects:
tyrosine kinase
Group A Streptococcus
Streptococcus pyogenes
post-translational modifications
tyrosine phosphorylation
dual-specificity tyrosine kinase
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.689246/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.689246/full

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