In Vitro and In Vivo Relevant Antineoplastic Activity of Platinum(II) Complexes toward Triple-Negative MDA-MB-231 Breast Cancer Cell Line

In Vitro and In Vivo Relevant Antineoplastic Activity of Platinum(II) Complexes toward Triple-Negative MDA-MB-231 Breast Cancer Cell Line

Two platinum complexes [Pt(HL3)Cl]·H<sub>2</sub>O (<b>3</b>) and [Pt(HL4)Cl]·H<sub>2</sub>O (<b>4</b>) containing <i>α-</i> and <i>β</i>-naphthyl groups, respectively, were investigated in more detail in vitro and in vivo for an...

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Bibliographic Details
Main Authors: Leide Laura Figueiredo Maciel, Marina Barreto Silva, Rafaela Oliveira Moreira, Ana Paula Cardoso, Christiane Fernandes, Adolfo Horn, João Carlos de Aquino Almeida, Milton Masahiko Kanashiro
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Pharmaceutics
Subjects:
breast cancer cells
platinum(II) complexes
cytotoxicity
apoptosis
antitumor
Online Access:https://www.mdpi.com/1999-4923/14/10/2013

Internet

https://www.mdpi.com/1999-4923/14/10/2013

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