Hepatoprotective agent tethered isoniazid for the treatment of drug-induced hepatotoxicity: Synthesis, biochemical and histopathological evaluation

The aim of the study was to investigate the protective effect of isoniazid–curcumin conjugate (INH–CRM) in INH-induced hepatic injury by biochemical analysis and histology examination of liver in Wistar rats. The biochemical analysis included determination of the levels of plasma cholesterol, trigly...

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Bibliographic Details
Main Authors: Charan Singh, Laxmikant Jodave, Tara Datt Bhatt, Manjinder Singh Gill, Sarasija Suresh
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Toxicology Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750014000985