Epstein–Barr Virus, But Not Human Papillomavirus, Is Associated With Preinvasive and Invasive Ocular Surface Squamous Neoplasias in Zambian Patients

Epstein–Barr Virus, But Not Human Papillomavirus, Is Associated With Preinvasive and Invasive Ocular Surface Squamous Neoplasias in Zambian Patients

BackgroundThe etiopathogenesis of ocular surface squamous neoplasia (OSSN) is not fully understood. We assessed the frequency of oncogenic viruses in OSSN by immunohistochemistry (IHC) and polymerase chain reaction (PCR) for human papillomavirus (HPV), Epstein–Barr virus (EBV), Merkel cell polyomavi...

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Bibliographic Details
Main Authors: Peter Julius, Stepfanie N. Siyumbwa, Phyllis Moonga, Fred Maate, Trevor Kaile, Gleb Haynatski, Veenu Minhas, Jazmine Snow, Kerstin Peterson, Patience Gihozo, Sam Streeter, Salan Kaur, Annika Evans, Daniela Gonzalez, Kandali Samwel, Guobin Kang, John T. West, Charles Wood, Peter C. Angeletti
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Oncology
Subjects:
ocular surface squamous neoplasia
human papillomavirus
Epstein–Barr virus
human immunodeficiency virus
Zambia
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.864066/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.864066/full

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