Mathematical model combined with microdosimetric kinetic model for tumor volume calculation in stereotactic body radiation therapy

Abstract We proposed a new mathematical model that combines an ordinary differential equation (ODE) and microdosimetric kinetic model (MKM) to predict the tumor-cell lethal effect of Stereotactic body radiation therapy (SBRT) applied to non-small cell lung cancer (NSCLC). The tumor growth volume was...

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Bibliographic Details
Main Authors: Hisashi Nakano, Takehiro Shiinoki, Satoshi Tanabe, Satoru Utsunomiya, Takeshi Takizawa, Motoki Kaidu, Teiji Nishio, Hiroyuki Ishikawa
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-38232-4