Hydrogen peroxide enhances transforming growth factor beta-2 induced epithelial–mesenchymal transition of ARPE-19 cells

Hydrogen peroxide enhances transforming growth factor beta-2 induced epithelial–mesenchymal transition of ARPE-19 cells

Abstract Background In the pathophysiology of the retina, the epithelial–mesenchymal transition and oxidative stress play key roles. To find a relationship between oxidative stress and diabetic retinopathy or proliferative retinopathy, we used an in-silico approach. We also used an in vitro investig...

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Bibliographic Details
Main Authors: Brijesh Gelat, Pooja Rathaur, Pooja Malaviya, Binita Patel, Abhay R. Vasavada, S. R. Kaid Johar
Format: Article
Language:English
Published: SpringerOpen 2023-11-01
Series:Beni-Suef University Journal of Basic and Applied Sciences
Subjects:
Epithelial–mesenchymal transition
Human retinal pigment epithelial cells
Transforming growth factors-β2
Hydrogen peroxide
Oxidative stress
ARPE-19
Online Access:https://doi.org/10.1186/s43088-023-00421-5

Internet

https://doi.org/10.1186/s43088-023-00421-5

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