Post-translational modifications on the retinoblastoma protein

Post-translational modifications on the retinoblastoma protein

Abstract The retinoblastoma protein (pRb) functions as a cell cycle regulator controlling G1 to S phase transition and plays critical roles in tumour suppression. It is frequently inactivated in various tumours. The functions of pRb are tightly regulated, where post-translational modifications (PTMs...

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Bibliographic Details
Main Authors: Linbin Zhou, Danny Siu-Chun Ng, Jason C. Yam, Li Jia Chen, Clement C. Tham, Chi Pui Pang, Wai Kit Chu
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Journal of Biomedical Science
Subjects:
Retinoblastoma
Phosphorylation
Ubiquitination
SUMOylation
Acetylation
Methylation
Online Access:https://doi.org/10.1186/s12929-022-00818-x

Internet

https://doi.org/10.1186/s12929-022-00818-x

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