Tumor-stroma proportion is associated with increased M2 macrophage abundance and predicts the resistance to immune checkpoint blockade in breast cancer

Tumor-stroma proportion is associated with increased M2 macrophage abundance and predicts the resistance to immune checkpoint blockade in breast cancer

Background: The tumor stroma has been reported to be associated with worse prognosis in several solid tumors, but its prognostic value in breast cancer (BRCA) is still undefined. Methods: In this research, multiple public and in-house patient cohorts were collected to demonstrate the clinical and im...

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Príomhchruthaitheoirí: Yincheng Liu, Ningyi Xue, Yuelin Liu, Jie Mei, Yun Cai, Zhenghui Wang, Hongxin Lin, Mengyun Wan, Ji Zhou, Tiansong Xia, Yichao Zhu, Shui Wang
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: Elsevier 2025-04-01
Sraith:Translational Oncology
Ábhair:
Breast cancer
Tumor stroma
Immunotherapy
Biomarker
Collagen
Rochtain ar líne:http://www.sciencedirect.com/science/article/pii/S1936523325000749

Ar líne

http://www.sciencedirect.com/science/article/pii/S1936523325000749

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