T-cell receptors binding orientation over peptide/MHC class I is driven by long-range interactions.

T-cell receptors binding orientation over peptide/MHC class I is driven by long-range interactions.

Crystallographic data about T-Cell Receptor - peptide - major histocompatibility complex class I (TCRpMHC) interaction have revealed extremely diverse TCR binding modes triggering antigen recognition. Understanding the molecular basis that governs TCR orientation over pMHC is still a considerable ch...

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Bibliographic Details
Main Authors: Mathias Ferber, Vincent Zoete, Olivier Michielin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3522592?pdf=render

Internet

http://europepmc.org/articles/PMC3522592?pdf=render

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