Secretory prostate apoptosis response (Par)‐4 sensitizes multicellular spheroids (MCS) of glioblastoma multiforme cells to tamoxifen‐induced cell death

Secretory prostate apoptosis response (Par)‐4 sensitizes multicellular spheroids (MCS) of glioblastoma multiforme cells to tamoxifen‐induced cell death

Glioblastoma multiforme (GBM) is the most malignant form of brain tumor and is associated with resistance to conventional therapy and poor patient survival. Prostate apoptosis response (Par)‐4, a tumor suppressor, is expressed as both an intracellular and secretory/extracellular protein. Though secr...

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Bibliographic Details
Main Authors: Jayashree C. Jagtap, D. Parveen, Reecha D. Shah, Aarti Desai, Dipali Bhosale, Ashish Chugh, Deepak Ranade, Swapnil Karnik, Bhushan Khedkar, Aaishwarya Mathur, Kumar Natesh, Goparaju Chandrika, Padma Shastry
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:FEBS Open Bio
Subjects:
Glioblastoma
Par-4
Drug resistance
Multicellular spheroids (MCS)
Tamoxifen
Cytotoxicity
Online Access:https://doi.org/10.1016/j.fob.2014.11.005

Internet

https://doi.org/10.1016/j.fob.2014.11.005

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