Plitidepsin as a successful rescue treatment for prolonged viral SARS-CoV-2 replication in a patient with previous anti-CD20 monoclonal antibody-mediated B cell depletion and chronic lymphocytic leukemia

Plitidepsin as a successful rescue treatment for prolonged viral SARS-CoV-2 replication in a patient with previous anti-CD20 monoclonal antibody-mediated B cell depletion and chronic lymphocytic leukemia

Abstract Background There is an urgent need for highly efficacious antiviral therapies in immunosuppressed hosts who develop coronavirus disease (COVID-19), with special concern for those affected by hematological malignancies. Case presentation Here, we report the case of a 75-year-old male with ch...

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Bibliographic Details
Main Authors: P. Guisado-Vasco, M. M. Carralón-González, J. Aguareles-Gorines, E. M. Martí-Ballesteros, M. D. Sánchez-Manzano, D. Carnevali-Ruiz, M. García-Coca, R. Barrena-Puertas, R. García de Viedma, J. M. Luque-Pinilla, G. Sotres-Fernandez, J. M. Fernández-Sousa, X. E. Luepke-Estefan, J. A. López-Martín, J. M. Jimeno
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Journal of Hematology & Oncology
Subjects:
Plitidepsin
Covid-19
SARS-CoV-2
Anti-CD20 monoclonal antibody
Prolonged viral replication
Chronic lymphocytic leukemia
Online Access:https://doi.org/10.1186/s13045-021-01220-0

Internet

https://doi.org/10.1186/s13045-021-01220-0

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