PAR2-Induced Tissue Factor Synthesis by Primary Cultures of Human Kidney Tubular Epithelial Cells Is Modified by Glucose Availability

PAR2-Induced Tissue Factor Synthesis by Primary Cultures of Human Kidney Tubular Epithelial Cells Is Modified by Glucose Availability

Coagulopathies common to patients with diabetes and chronic kidney disease (CKD) are not fully understood. Fibrin deposits in the kidney suggest the local presence of clotting factors including tissue factor (TF). In this study, we investigated the effect of glucose availability on the synthesis of...

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Bibliographic Details
Main Authors: Tyrone L. R. Humphries, Kunyu Shen, Abishek Iyer, David W. Johnson, Glenda C. Gobe, David Nikolic-Paterson, David P. Fairlie, David A. Vesey
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
protease
glucose
PAR2
tissue factor
kidney tubular epithelial cells
diabetes
Online Access:https://www.mdpi.com/1422-0067/22/14/7532

Internet

https://www.mdpi.com/1422-0067/22/14/7532

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