Inflammasome‐induced extracellular vesicles harbour distinct RNA signatures and alter bystander macrophage responses

Inflammasome‐induced extracellular vesicles harbour distinct RNA signatures and alter bystander macrophage responses

Abstract Infectious organisms and damage of cells can activate inflammasomes, which mediate tissue inflammation and adaptive immunity. These mechanisms evolved to curb the spread of microbes and to induce repair of the damaged tissue. Chronic activation of inflammasomes, however, contributes to non‐...

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Bibliographic Details
Main Authors: Christina F. Budden, Linden J. Gearing, Romina Kaiser, Lena Standke, Paul J. Hertzog, Eicke Latz
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:Journal of Extracellular Vesicles
Subjects:
cell communication
extracellular vesicle
inflammasome
inflammation
interferon β
nucleotide‐binding oligomerization domain (NOD)‐containing protein with a pyrin domain (NLRP3)
Online Access:https://doi.org/10.1002/jev2.12127

Internet

https://doi.org/10.1002/jev2.12127

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