TAOK3 limits age-associated inflammation by negatively modulating macrophage differentiation and their production of TNFα

Abstract Background Human aging is characterized by a state of chronic inflammation, termed inflammaging, for which the causes are incompletely understood. It is known, however, that macrophages play a driving role in establishing inflammaging by promoting pro-inflammatory rather than anti-inflammat...

Full description

Bibliographic Details
Main Authors: Alexandre Poirier, Chenyue Wu, Ana Maria Hincapie, Zuzet Martinez-Cordova, Belma Melda Abidin, Michel L. Tremblay
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Immunity & Ageing
Subjects:
Online Access:https://doi.org/10.1186/s12979-023-00350-y