TAOK3 limits age-associated inflammation by negatively modulating macrophage differentiation and their production of TNFα
Abstract Background Human aging is characterized by a state of chronic inflammation, termed inflammaging, for which the causes are incompletely understood. It is known, however, that macrophages play a driving role in establishing inflammaging by promoting pro-inflammatory rather than anti-inflammat...
Main Authors: | Alexandre Poirier, Chenyue Wu, Ana Maria Hincapie, Zuzet Martinez-Cordova, Belma Melda Abidin, Michel L. Tremblay |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-07-01
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Series: | Immunity & Ageing |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12979-023-00350-y |
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